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Dosages of less than 5 mg prednisolone per day are not significant and no steroid cover is required. It is not used as an anesthetic for trauma. What if I need to take it too close to bedtime? It is not recommended to take prednisone in high doses during the morning due to increasing insomnia. The dose should still be low enough to prevent insomnia and hypoglycemia, but excessive use of prednisone can result in adverse effects including: Decreased alertness, Loss of coordination, Headaches, Nervousness and tremors, Loss of sleep. Other Warnings Hypoglycemia: Prednisone may cause hypoglycemia due to its diuretic effect. If hypoglycemia develops, reduce the dose of prednisone. Check your sugar level as a sign of hypoglycemia. Use of this product with other drugs: Use with all prescriptions to manage diabetes. Ask your healthcare provider before using Prednisone with other drugs. Tell your healthcare provider if you are using any other diabetes medications such as metformin, sulfonylureas, sulfonylureas sulfonylureate, metformin monotherapy or metformin with sulfonylureas sulfonylureate, sulfonylureas with sulfanylation. These medicines may interact or cause unwanted effects or side effects. Never start using prednisone if you are taking any drugs used to treat diabetes, including prescription or over-the-counter medicine that contain phenothiazines. Ask your healthcare provider about how you may safely and properly use this product with other diabetes drugs, including medicines used to treat blood sugar control and antidiabetic medications. It is not known if other medications will interact with prednisone or if prednisone is harmful or dangerous to other people. Always tell your healthcare provider about all medicines you use, including products purchased over the counter. Do not start, stop, or change the dose of any medicine without first talking to your healthcare provider. What happens if I miss a dose? Take the missed dose as soon as you think about it. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking Prednis Similar articles: